Lisheng Wang Selected Research

Matrines

1/2020	New modification strategy of matrine as Hsp90 inhibitors based on its specific L conformation for cancer treatment.
1/2019	Research advances on anticancer activities of matrine and its derivatives: An updated overview.
9/2018	Design, synthesis, biological evaluation and structure-activity relationship of sophoridine derivatives bearing pyrrole or indole scaffold as potential antitumor agents.
1/2018	Design, synthesis and biological evaluation of matrine derivatives as potential anticancer agents.
9/2017	Synthesis, biological evaluation and mechanism studies of matrine derivatives as anticancer agents.
2/2017	Matrine derivative YF-18 inhibits lung cancer cell proliferation and migration through down-regulating Skp2.
10/2016	Synthesis and biological evaluation of matrine derivatives containing benzo-α-pyrone structure as potent anti-lung cancer agents.
1/2016	Synthesis and biological evaluation of matrine derivatives as anti-hepatocellular cancer agents.
11/2014	[Inhibitive effect of matrine modification X on the growth of human nasopharyngeal carcinoma CNE2 cell xenografts in nude mice].
1/2014	14-Thienyl methylene matrine (YYJ18), the derivative from matrine, induces apoptosis of human nasopharyngeal carcinoma cells by targeting MAPK and PI3K/Akt pathways in vitro.

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Lisheng Wang Research Topics

Disease

50	Neoplasms (Cancer) 02/2022 - 05/2003
13	Breast Neoplasms (Breast Cancer) 01/2022 - 08/2013
9	Infections 11/2022 - 08/2005
8	Carcinogenesis 01/2022 - 01/2015
8	Triple Negative Breast Neoplasms 01/2022 - 12/2016
7	Lung Neoplasms (Lung Cancer) 02/2022 - 01/2015
6	Inflammation (Inflammations) 01/2022 - 08/2008
6	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2015
6	Leukemia 12/2020 - 08/2007
5	Neoplasm Metastasis (Metastasis) 01/2022 - 10/2017
5	Stomach Neoplasms (Stomach Cancer) 01/2021 - 12/2013
4	Fibrosis (Cirrhosis) 03/2022 - 04/2009
4	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 03/2013
4	Cognitive Dysfunction 03/2021 - 12/2018
4	Hypoxia (Hypoxemia) 08/2020 - 12/2015
4	Hemorrhage 01/2015 - 02/2008
3	Lymphoma (Lymphomas) 01/2022 - 07/2011
3	Respiratory Syncytial Virus Infections 01/2021 - 01/2017
3	Pneumonia (Pneumonitis) 01/2021 - 01/2018
3	Ischemic Stroke 01/2021 - 09/2016
3	Ulcerative Colitis 12/2015 - 03/2013
3	Colitis 12/2015 - 03/2013
3	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 06/2015 - 02/2012
3	Thrombosis (Thrombus) 12/2009 - 02/2008
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 03/2008 - 08/2007
2	COVID-19 04/2022 - 07/2020
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 10/2016
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 12/2021 - 01/2020
2	Disease Progression 11/2021 - 07/2020
2	Body Weight (Weight, Body) 01/2021 - 04/2011
2	Weight Loss (Weight Reduction) 01/2021 - 04/2011
2	Reperfusion Injury 03/2018 - 12/2013
2	Heart Failure 01/2018 - 02/2014
2	Liver Neoplasms (Liver Cancer) 10/2016 - 01/2016
2	Hepatocellular Carcinoma (Hepatoma) 06/2016 - 07/2008
2	Nasopharyngeal Carcinoma 11/2014 - 01/2014
1	Graft vs Host Disease (Graft-Versus-Host Disease) 07/2022

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2005
11	MatrinesIBA 01/2020 - 06/2012
10	MicroRNAs (MicroRNA)IBA 01/2022 - 03/2008
8	Pharmaceutical PreparationsIBA 01/2022 - 12/2015
7	CytokinesIBA 01/2022 - 08/2008
7	Biological ProductsIBA 01/2022 - 09/2015
5	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2022 - 01/2020
5	Therapeutic UsesIBA 01/2020 - 12/2015
5	CateninsIBA 06/2019 - 10/2015
5	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 01/2018 - 07/2008
4	Messenger RNA (mRNA)IBA 03/2022 - 08/2007
4	VaccinesIBA 11/2021 - 08/2012
4	LigandsIBA 01/2021 - 10/2017
4	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2020 - 12/2015
3	Cisplatin (Platino)FDA LinkGeneric 02/2022 - 01/2018
3	Small Interfering RNA (siRNA)IBA 02/2022 - 09/2015
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2017
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2021 - 01/2017
3	Sirtuin 1IBA 12/2020 - 02/2012
3	DecorinIBA 01/2019 - 01/2017
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 01/2017
3	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 04/2011
3	Imatinib Mesylate (Gleevec)FDA Link 06/2015 - 02/2012
3	AnticoagulantsIBA 12/2009 - 02/2008
3	HirudinsIBA 12/2009 - 02/2008
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 03/2022 - 03/2018
2	Long Noncoding RNAIBA 12/2021 - 01/2020
2	DNA (Deoxyribonucleic Acid)IBA 10/2021 - 03/2013
2	AntioxidantsIBA 05/2021 - 01/2019
2	GraphiteIBA 01/2021 - 01/2021
2	Molecularly Imprinted PolymersIBA 01/2021 - 01/2021
2	Verteporfin (Visudyne)FDA Link 01/2021 - 10/2019
2	sphingosine kinaseIBA 12/2020 - 07/2008
2	Chimeric Antigen ReceptorsIBA 01/2020 - 01/2018
2	AntibodiesIBA 01/2019 - 01/2016
2	PerforinIBA 01/2019 - 01/2017
2	Granzymes (Granzyme)IBA 01/2019 - 01/2017
2	buyang huanwuIBA 01/2019 - 12/2013
2	Oxygen (Dioxygen)IBA 01/2019 - 03/2018
2	Respiratory Syncytial Virus VaccinesIBA 01/2019 - 01/2017
2	AntigensIBA 01/2018 - 05/2003
2	Sirolimus (Rapamycin)FDA Link 01/2018 - 12/2015
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2018 - 09/2007
2	NucleotidesIBA 11/2017 - 03/2008
2	Cadherins (E-Cadherin)IBA 04/2017 - 01/2016
2	UbiquitinIBA 04/2017 - 08/2007
2	SB 743921IBA 10/2016 - 06/2015
2	Caspase 3 (Caspase-3)IBA 10/2016 - 01/2014
2	Interleukin-10 (Interleukin 10)IBA 12/2015 - 12/2015
2	Transcription Factors (Transcription Factor)IBA 08/2013 - 07/2011
2	Blood Glucose (Blood Sugar)IBA 04/2011 - 04/2009
2	Thrombin FDA Link 12/2009 - 11/2008
2	Staphylococcus aureus auR protein (staphylokinase)IBA 12/2009 - 11/2008
2	LipidsIBA 04/2009 - 08/2005
1	Peptides (Polypeptides)IBA 11/2022

Therapy/Procedure

20	Therapeutics 02/2022 - 07/2011
4	Transplantation 02/2022 - 08/2012
3	Immunotherapy 01/2022 - 06/2019
3	Drug Therapy (Chemotherapy) 01/2022 - 01/2016
3	Home Nursing (Nursing, Home) 03/2021 - 05/2020
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2019 - 11/2017
2	Ligation 12/2018 - 01/2015
1	Hematopoietic Stem Cell Transplantation 07/2022